The 21-year-old Spaniard went down 4-6, 2-6 against wild card Birrell, 20, and was knocked out of the first grand slam of the year.
Fellow Spaniard Sara Sorribes Tormo was also knocked out of the first round of the tournament after she lost 3-6, 2-6 to Estonia's Anett Kontaveit, reports Efe news.
Spain will now be resting its hopes for the women's titles on Garbine Muguruza, Carla Suarez Navarro and Lara Arruabarrena, who are all set to play on Tuesday.
(This story has not been edited by Social News XYZ staff and is auto-generated from a syndicated feed.)
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