The driver and another occupant of the car were rescued by police with the help of locals.
The tragic incident occurred in Pillivagu near Karegam in Nizamabad district when the car was crossing the stream.
Efforts were on to trace the woman and children, aged under seven. Two-year-old twins and a 10-month-old baby were among those washed away.
The incident occurred when the woman and children were going to a hospital at Pitlam in the same district.
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