The Dow Jones Industrial Average on Friday fell 64.79 points, or 0.35 per cent, to 18,327.67, Xinhua news agency reported.
The S&P 500 lost 7.45 points, or 0.34 per cent, to 2,169.73. The Nasdaq Composite Index was down 17.01 points, or 0.32 per cent, to 5,322.51.
US stocks kept rising Thursday, with all three major indices logging a three-day winning streak, as Wall Street continued to cheer over the Federal Reserve's decision to leave its interest rates unchanged.
The Nasdaq extended record run Thursday, refreshing its intraday and closing records for the second time in the past three sessions.
Meanwhile, investors were still sifting through the Fed's policy meeting ended early this week.
"The Committee judges that the case for an increase in the federal funds rate has strengthened but decided, for the time being, to wait for further evidence of continued progress toward its objectives," the Fed said in a statement after the conclusion of its two-day policy meeting.
"The economy has a little more room to run than might have been previously thought. That's good news ... we don't see the economy as overheating now," Fed Chair Janet Yellen said at a press conference following the release of the statement, suggesting the Fed had the opportunity to allow the labor market to continue to improve without running a hot economy.
On the economic front, the seasonally adjusted Markit Flash US Manufacturing Purchasing Managers' Index fell from August's reading of 52.0 to 51.4 in September, missing market consensus.
