Playing without superstar Cristiano Ronaldo, Portugal lost 0-2 away to Switzerland through goals from Breel Embolo and Ahmed Mehmedi here on Tuesday, reports Efe.
The French had to settle for a 0-0 draw in Belarus thanks to a fine performance from the home team goalkeeper Andrei Gorbunov.
Belgium, in the first competitive match under new coach Roberto Martinez, cruised to a 3-0 away victory over Cyprus on a pair of goals by Romelu Lukaku and one from Yannick Carrasco.
Sweden took a 1-0 lead at home over the Netherlands, but midfielder Wesley Sneijder equalised to salvage a 1-1 draw for the visitors.
In another qualifier, Albania topped Macedonia 2-1.
Bosnia-Herzegovina pounded Estonia 5-0 and Greece romped to a 4-1 victory over Gibraltar.
Andorra fell 1-0 at home to Latvia. Hungary could manage only a scoreless draw with Faroe Islands.
Bulgaria beat Luxembourg 4-3 on a stoppage time goal by Alexandar Tonev.
