Saina, who bowed out of the Rio Olympics after the first round, has been battling with a knee problem for quite some time.
The 26-year-old, who was admitted to a hospital in Hyderabad on Thursday, informed on Twitter about her surgery.
"Surgery tomorrow morning at 6 a.m. friends pls pray for me," Saina's tweet read.
Saina revealed that her knee started troubling just before the Olympics and further worsened after training and her first round match against Marija Ulitina.
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