Trailing the Panchkula golfer by a margin of eight shots is Gursimar Badwal with a total score of 150 after the midway stage.
Amandeep carded two birdies on the second and sixth holes with an equal number of bogeys on the first and seventh in her front nine.
She carded two more birdies on the 10th and 11th holes, but two dropped shots on the 14th and 17th which prevented her from carding an under-par score in the round as she finished with a total score of 142.
She has a big lead of eight shots going into the final round and will be eyeing her second title of the season.
Badwal carded three over 75 in the second round to retain her second position. She carded two birdies on the fourth and sixth holes while dropping a single shot on the seventh hole in her front nine.
The professional from Kapurthala, however, could not sustain the momentum on her return and carded two bogeys on the 13th and 18th holes along with a double on the 16th.
Kolkatas Neha Tripathi is placed third with a total score of 153 after 36 holes while local girls Sharmila Nicollet and Trisha Sunil are tied fourth with identical totals of 154.
Jaipurs Afshan Fatima and amateur Suchitra Ramesh are tied sixth at 155, followed by Delhis Ankita Tiwana and Punes Shweta Galande in tied eighth at 156.
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